Reaction mass of 4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide and 4-[[4-(aminocarbonyl)phenyl]azo]-3-hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide

Nanomaterial dustiness

Administrative data

Endpoint:

nanomaterial dustiness

Type of information:

experimental study

Adequacy of study:

key study

Study period:

18.09.2020 - 14.10.2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods

Remarks:

according to DIN EN 17199-3

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Report date:

2020

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: EN 17199-3

Version / remarks:

measurement of dustiness of bulk materials that contain or release respirable NOAA or other
respirable particles - Part 3: Continuous drop method

GLP compliance:

no

Type of method:

continuous drop

Sampling:

The product was used without special pre-treatment, such as drying or similar.

Test material

Test material information

Constituent 1

Reference substance name:

4-[(1E)-2-(4-carbamoylphenyl)diazen-1-yl]-3-hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide; 4-[(1E)-2-(4-carbamoylphenyl)diazen-1-yl]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide

EC Number:

911-436-4

Cas Number:

61932-63-6

Molecular formula:

not applicable

IUPAC Name:

4-[(1E)-2-(4-carbamoylphenyl)diazen-1-yl]-3-hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide; 4-[(1E)-2-(4-carbamoylphenyl)diazen-1-yl]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide

Test material form:

solid: nanoform, no surface treatment

Details on test material:

Pigment Red 210 nanoform

Results and discussion

Dustiness index

Dustiness index 1

Key result

Mean:

38 398.8 other: 1/mg

St. dev.:

0 other: not relevant

Remarks on result:

other:

Remarks:

dustiness index as number of airborne particles per mg in the nanoscale (10 nm - 100 nm)

Dustiness index 2

Mean:

19 453 other: N/cm3

St. dev.:

0 other: not relevant

Remarks on result:

other: number of airborne nanoparticles per cm3

Any other information on results incl. tables

Measurement duration: 10 min

temperature: 20°C, rel. air humidity 60%

table 1: summary SMPS (sanning mobility particle sizer)

Range [nm]  Mean [nm]  Concentration [N/cm³] ICD [1/mg]   ECD [1/mg·s]  10-100 56,4 19453,0 38398,8 64,0  100-417 204,8 38439,1 75876,1 126,5  10-417 154,9 57892,1 114274,9 190,5

ICD: dustiness index as number of airborne particles per mg

ECD: emission rate as number of particles per mg per second

mean: average particle diameter in nm

N: number of airborne particles

table 2: summary OPS (optical particle sizer)

Range [µm]  Mean [µm]  Concentration [N/ cm3] ICD[1/mg]   ECD[1/mg x s]  0.3 - 10 4,4 1208,6 2385,7 4,0

Applicant's summary and conclusion

Executive summary:

The dusting behaviour of the test material was investigated using DIN EN 17199 -3: 2019 -12 "workplace exposure - measurement of dustiness of bulk materials that contain or release respirable nano objects and their aggregates and agglomerates or other respirable particles- Part 3: Continuous drop method".

The dust released by the falling test material was measured by a scanning mobility particle sizer (SMPS,10 - 417 nm) and an optical particle sizer (3 - 10 µm). The counterflow was provided by cleaned, almost particle-free air.

The SMPS counted 19453.0 particles per cm3 in the nanoscale 10 - 100 nm. corresponding to a dustiness index of 38398.8 particles per mg in the nanoscale 10 - 100 nm. The mean size of the nanoparticles in the range 10 - 100 nm 417 nm was 56.4.

The OPS (0.3 - 10 µm) counted 1208.6 particles per cm3 corresponding to a dustiness index of 2385.7 particles per mg. The mean size of the particles was 4.4 µm.