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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

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Endpoint:
melting point/freezing point
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Justification for type of information:
For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Reason / purpose for cross-reference:
read-across source
Key result
Melting / freezing pt.:
97 °C
Atm. press.:
1 021 hPa
Conclusions:
The melting point was determined by an experimental study conducted according to OECD TG 102. The melting point of D-lactide was determined to be 97 °C at 102.1 +/- 0.1 kPa.
Executive summary:

The melting temperature of the test substance were determined using differential scanning calorimetry (DSC). This technique records the difference in heat flow to two crucibles, one filled with test substance and the other filled with an inert reference material, while these crucibles are subjected to a controlled temperature programme. When the test substance undergoes a transition, such as melting or evaporation, it is indicated by a deviation from the base line of the heat-flow record. Because melting and evaporation are processes in which heat is consumed, for these processes the deviation from the base line is in the endothermic direction. The melting temperature or boiling temperature (if any) of the test substance is evaluated from the DSC curve as the extrapolated onset temperature of the endothermic melting or evaporation peak.

The melting temperature of the test substance calculated as the mean value of all five experiments is 97 °C at 102.1 +/- 0.1 kPa.

This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.

Endpoint:
melting point/freezing point
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Justification for type of information:
For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Reason / purpose for cross-reference:
read-across source
Key result
Melting / freezing pt.:
97 °C
Atm. press.:
1 019 hPa
Conclusions:
The melting point was determined by an experimental study conducted according to OECD TG 102. The melting point of L-lactide was determined to be 97 °C at 101.9 +/- 0.1 kPa.
Executive summary:

The melting temperature of the test substance were determined using differential scanning calorimetry (DSC) in an experimental study conducted according to OECD TG 102. This technique records the difference in heat flow to two crucibles, one filled with test substance and the other filled with an inert reference material, while these crucibles are subjected to a controlled temperature programme. When the test substance undergoes a transition, such as melting or evaporation, it is indicated by a deviation from the base line of the heat-flow record. Because melting and evaporation are processes in which heat is consumed, for these processes the deviation from the base line is in the endothermic direction. The melting temperature or boiling temperature (if any) of the test substance is evaluated from the DSC curve as the extrapolated onset temperature of the endothermic melting or evaporation peak.

The melting temperature of the test substance calculated as the mean value of all five experiments is 97 °C at 101.9 +/- 0.1 kPa.

This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13

Description of key information

The melting temperature of L-lactide and D-lactide were determined by using DSC. The outcome was the same for the two lactides and is fully valid for dilactide as dilactide is a mixture of D- and L-lactide isomers. The melting temperature of both test substances were determined to be 97 °C or 370 K. The experiments were performed under a flow of nitrogen and at atmospheric pressure.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
97 °C

Additional information