Registration Dossier

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Meets national standard methods

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2006
Report Date:
2006

Materials and methods

Type of study / information:
Type of experience: Occupational exposure of workers at production plants
Endpoint addressed:
not applicable
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Collection of workplace exposure data
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Diethanolamine
- no further data

Method

Exposure assessment:
measured
Details on exposure:
TYPE OF EXPOSURE: workplace measurements

TYPE OF EXPOSURE MEASUREMENT: Area air sampling

EXPOSURE PERIOD: January 2001-December 2006

Results and discussion

Results:
Results: At present DEA is produced in one production plant and is further processed within 8 other operations and plants at the BASF SE.
The results of the 53 measurements are summarized as follows:
Overall Range of values: < 0.019 to 0.062 mg/m3
Medium value: 0.011 mg/m3
50% percentile: 0.003 mg/m3
90% percentile: 0.035 mg/m3
95% percentile: 0.051 mg/m3

Highest value for production plant: 0.026 mg/m3
Highest value at filling station: 0.062 mg/m3

No detailed differentiation was considered necessary since all measured values were far below the MAK-value and about 90 % of all recorded values were below limits of detection.

Precautions taken at the production plant:
DEA is handled in technically closed processes at all plants and operations. Short-term tasks showing in general a potential for exposure are limited to sample taking, analytical work, filter changes or filling operations.   Direct skin contact is avoided by protective gloves (nitrile rubber or PVC).

Any other information on results incl. tables

Results:
At present DEA is produced in one production plant and is further processed within 8 other operations and plants at the BASF SE

The results of the 53 measurements are summarized as follows:

Overall Range of values: < 0.019 to 0.062 mg/m3
Medium value: 0.011 mg/m3
50% percentile: 0.003 mg/m3
90% percentile: 0.035 mg/m3
95% percentile: 0.051 mg/m3

Highest value for production plant: 0.026 mg/m3
Highest value at filling station: 0.062 mg/m3
 

No detailed differentiation was considered necessary since all measured values were far below the MAK-value and about 90 % of all recorded values were below limits of detection.

Precautions taken at the production plant:

DEA is handled in technically closed processes at all plants and operations.

Short-term tasks showing in general a potential for exposure are limited to sample taking, analytical work, filter changes or filling operations.
 

Direct skin contact is avoided by protective gloves (nitrile rubber or PVC).

Applicant's summary and conclusion