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Short-term toxicity to aquatic invertebrates

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Description of key information

Acutely harmful to aquatic invertebrates

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
30.1 mg/L
EC50/LC50 for marine water invertebrates:
378 mg/L

Additional information

A static acute immobilisation study performed according to ASTM Standard E729-80 with Ceriodaphnia dubia as test organism was selected as key study (Cowgill et al., 1985). At 24 °C, the 48-h EC50 was determined to be 30.1 mg/L (95% CL: 22.2-39.1 mg/L).

The lowest reliable value for acute toxicity to Daphnia magna was reported from a static test according to US EPA Guideline 600/3-75-009 (LeBlanc, 1980). Based on nominal concentrations, the 48-h EC50 was 55 mg/l. However, since measured pH values ranged from 7.4 to 9.4, alkaline pH effects might have contributed to the observed mortality. 

In addition, the acute toxicity of DEA to Daphnia magna was investigated in a 48-hour static test according to OECD TG 202. Based on nominal concentrations, the 48 hour EC50 was 171 mg/l (Zurita et al., 2005).

Further, the effect of DEA on Hyalella azteca was studied according to an Environment Canada method (PTAC, 2006). 50 animals were exposed to a series of 5 test concentrations and observed over 96 h and dead neonates counted after 48 and 96 h. The 96-h LC50 was determined to be 344 mg/L (95% CL: 312 -377 mg/L; nominal, analytically verified).

In a study according to "APAT and IRSA-CNR. Analytical methods for waters. Report 29, 2003" the effect of DEA to marine organisms was evaluated with Artemia franciscana as test species. The 24-h EC50 was determined to be 378 mg/L (Libralato et al., 2010).