Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-817-4 | CAS number: 74-87-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Chloromethane is gaseous and the primary environmental compartment to which it partition is air. The substance is not harmful to invertebrates.
Key value for chemical safety assessment
Additional information
Chloromethane is a gaseous substance and primary environmental compartment to which it partition is air. Therefore, thesubstance will evaporate from the water body. As such significant toxicological effects on aquatic organisms are not expected.
One reliable Daphnia magna study from DOW (2000) according to OECD 202 is available and was conducted under static-renewal test conditions (renewal at 24h) in a closed (no headspace) system and analysis of exposure solutions following 24 hours of aging in closed vessels without headspace showed little to no loss of test substance. This studies indicate chloromethane is of low toxicity to Daphnia magna (EC50 = 200 mg/L) and the reported results are comparable to the 48-h LC50 of 394 mg/L for daphnia predicted by ECOSAR. The ECOSAR model is a reliable and valid QSAR model to apply to chloromethane because it is based on a related chemical dataset. All data show toxicities of chloromethane far in excess of natural occurring concentrations. The substance is not harmful to invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
