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EC number: 267-051-0
CAS number: 67774-74-7
Results of Skin Irritation Study
Time after patch removal
This study examined the potential of the test substance to cause skin
irritation. 6 rabbits were exposed to undiluted test substance on shave
skin for 4 hrs. After the exposure the animals were scored for skin
irritation, and were scored again at 24, 48, and 72 after end of
exposure. Since symptoms were not fully resolved, further observations
were made at 5 and 7 days after end of exposure. At the 24 hr
observation, all animals showed signs of erythema (maximum score of 2),
and one animal showed signs of edema (score of 1). There were no signs
of edema in any animal at the 48 hr observation. Erythema persisted in
all animals through day 5, and in 3 of the animals, erythema was not
fully resolved at the end of the experiment on day 7. Though all
symptoms of irritation were mild, the irritation was not fully
reversible within the study period.
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