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EC number: 267-051-0 | CAS number: 67774-74-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 Jun 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 7.9
- Temp.:
- 25 °C
- Remarks on result:
- other: pH not reported.
- Details on results:
- Being a multiconstiuent substance, peaks were observed at 9.73, 11.91, 12.10, 14.67, 16.47, 18.02, 18.29, and 18.75 minutes (average of two injections). The log Pow for each fraction was 7.09, 7.56, 7.60, 8.03, 8.28, 8.47, 8.50, and 8.55 respectively, giving a weighted average log Pow of 7.9.
- Conclusions:
- The log Pow of the test substance is 7.9 at 25 ˚C
- Executive summary:
The 1-octanol / water partition coefficient (Pow) of the test substance has been determined in accordance with OECD TG 107 and in compliance with GLP. The octanol / water partition coefficient (Pow) was determined to be 7.9 at 25 °C
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 15 Jan 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 6.4
- Temp.:
- 25 °C
- Remarks on result:
- other: pH not reported.
- Details on results:
- Being a multiconstiuent substance, peaks were observed at 8.52, 10.35, 12.73, and 14.55 minutes (average of two injections). The log Pow for each fraction was 6.09, 6.30, 6.51, and 6.64 respectively, giving a weighted average log Pow of 6.4.
- Conclusions:
- The log Pow of the test substance is 6.4 at 25 ˚C.
- Executive summary:
The 1-octanol / water partition coefficient (Pow) of the test substance has been determined in accordance with OECD TG 107 and in compliance with GLP. The octanol / water partition coefficient (Pow) was determined to be 6.4 at 25 °C.
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 15 Jan 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 6.4
- Temp.:
- 25 °C
- Remarks on result:
- other: pH not reported.
- Details on results:
- Being a multiconstiuent substance, peaks were observed at 8.62, 10.45, 12.77, and 15.31 minutes (average of two injections). The log Pow for each fraction was 6.10, 6.31, 6.52, and 6.69 respectively, giving a weighted average log Pow of 6.4.
- Conclusions:
- The log Pow of the test substance is 6.4 at 25 ˚C.
- Executive summary:
The 1-octanol / water partition coefficient (Pow) of the test substance has been determined in accordance with OECD TG 107 and in compliance with GLP. The octanol / water partition coefficient (Pow) was determined to be 6.4 at 25 °C.
Referenceopen allclose all
Description of key information
The Partition coefficient of the test subtstance was conducted according to OECD 117 by using HPLC and the Log Kow was found to be 6.4 - 7.9.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 7.9
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
