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Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
Fetal exposure to endocrine disruptors in Japanese pregnant women.
Author:
Hirahara F, Sumiyoshi Y, Yamanaka M, Sugawara T, Ishikawa H, Endoh M, Andoh N, Takahashi T & Mori C
Year:
2002
Bibliographic source:
Congenital Anomalies Kyoto. 42: 257.

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Blood samples were obtained from pregnant women during the first, second and third trimesters and umbilical cord blood samples were drawn during their deliveries. Immunoreactive BPA was measured by ELISA. (As discussed in the abstract)

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Results:
In maternal blood, the mean BPA level was 0.290 ng/ml; in the umbilical cord samples, the mean BPA level was 1.476 ng/ml. (As discussed in the abstract)

Applicant's summary and conclusion

Executive summary:

Blood samples were obtained from pregnant women during the first, second and third trimesters and umbilical cord blood samples were drawn during their deliveries. Immunoreactive BPA was measured by ELISA. In maternal blood, the mean BPA level was 0.290 ng/ml; in the umbilical cord samples, the mean BPA level was 1.476 ng/ml. (As discussed in the abstract)