Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-155-0
CAS number: 64742-52-5
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil of at least 100 SUS at 100°F (19cSt at 40°C). It contains relatively few normal paraffins.
absorption and kinetics of a sample of P15H white oil was investigated
in nine female volunteers (age 18 -35 years) following single oral
administration. The white oil was administered in a gelatine capsule,
with each capsule containing on average 71.2 mg (min 70 mg, max 74 mg)
P15H - tetracosane mix. After adjustment for body weight, the subjects
received on average 1.09 +/- 0.12 mg mix/kg BW. After correction for the
tetracosane content of the mixture (8%), the dose of P15H oil was on
average 1.00 +/- 0.11 mg/kg BW. Blood samples were taken prior to
treatment, and then at regular intervals over 7 days (that is: 1, 2, 4,
8, 24, 48, 72, 96 and 168 hours post-dose). The samples wereextracted
with hexane followed by analysis using two-dimensional gas
chromatography-mass spectrometry (GCxGC-MS). No clinical signs or
adverse symptoms were reported by the volunteers. Results of blood
analyses showed that the concentration of P15H white oil in the blood
was below the average within laboratory detection limit (0.163 ug/mL) at
all timepoints, hence no kinetic analyses were possible. At
a dose 2-4 times that estimate daily intake, no appreciable absorption
of P15H oil occurred.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again