Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-090-8 | CAS number: 64741-88-4 A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100°F (19cSt at 40°C).
Table 1. Mean Dermal Irritation Scores
Exposure time (hours)
Exposure unit (Values*)
Subtotal = 1.17
Subtotal = 1.17
Total = 2.34
Primary Irritation Score = (2.34/4) = ~0.6
*Average value of animals recorded for dermal irritation in the study.
In a primary dermal irritation study, 6 New Zealand White rabbits (3 male/3 female) were dermally administered 0.5 mL solvent dewaxed light paraffinic oil under occlusive wrap for 24-hours. After the exposure period, the bandages were removed and test sites were wiped with guaze sponges. The animals were observed thereafter and dermal irritation was scored using the method of Draize at 24 hours, 72 hours and on Day 7 post-exposure.
Edema was not apparent in male or female rabbits at any observation point. Very slight erythema (1) was evident in all male and female rabbits at the 24 hour observation point. Very slight erythema (1) was observed in only 1 male rabbit by the 72 hour observation point and no irritation was visible in any test animal by the end of the 7-day observation period. No differences in irritation were observed between intact and abraded skin sites.
Solvent dewaxed light paraffinic oil is not considered to be irritating to the skin of rabbits.
This study is classified as 'reliable with restriction' because although the study is well documented and scientifically acceptable, the results for the 48-hour observation period were not reported as recommended by acceptable guidelines. Adverse systemic effects such as signs of clinical toxicity and body weight were not conducted and/or reported.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again