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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Accepted procedure for estimating partition coeficients based on solubility values, no restrictions, fully adequate for assessment.
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
no
Type of method:
other: estimation method
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
> 5.5
Temp.:
20 °C
Remarks on result:
other: pH not applicable (estimation method)

The partition coefficient was calculated as the quotient of the n-octanol solubility and the water solubility.

Description of key information

Log Pow > 5.5 at 20°C (based on n-octanol solubility (OECD 117, EU A8) and water solubility (OECD 105, flask method)

Key value for chemical safety assessment

Additional information

Value was calculated based on solubilities determined in water and octanol.