Registration Dossier
Registration Dossier
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EC number: 606-964-4 | CAS number: 222408-90-4
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study according EU/OECD guideline.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2,4-triazolidine-3-thione
- EC Number:
- 606-964-4
- Cas Number:
- 222408-90-4
- Molecular formula:
- C14 H17 CI2 N3 O S
- IUPAC Name:
- 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2,4-triazolidine-3-thione
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- yes
Results and discussion
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 9
- Temp.:
- 50 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 2.14 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: linear regression
- pH:
- 7
- Temp.:
- 50 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 1.99 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: linear regression
- pH:
- 4
- Temp.:
- 50 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 2.23 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: linear regression
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
