Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The reported  solubility of 1,3-butadiene is 0.735g/l at 20˚C. 

Key value for chemical safety assessment

Water solubility:
735 mg/L
at the temperature of:
20 °C

Additional information

This study by McAuliffe (1966) predates the implementation of GLP and standard guidelines. The method is described in detail and is considered appropriate for determining the solubility of a gaseous substance. In addition, this reference was used as the key study in the EU RAR (2002) for 1,3-butadiene. It should be noted that the solubility was measured in a closed system with an equilibrium between the vapour and water phase. This is an artificial situation, and in the environment the observed solubility would be expected to be much less. This was also supported by data reported in the International Chemical Safety Card (WHO ICSC, 2000).