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Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance is insoluble
other:

Description of key information

According to Regulation (EC) 1907/2006 Annex IX, column 2, section 7.16, the study does not need to be conducted because the substance is insoluble. The water solubility of TiO2 is <1 mg/L (please refer to section 4.8 water solubility).

Furtheremore, the substance does not contain relevant functional groups for which an assessment of the dissociation behaviour would provide information for risk assessment purposes. Therefore, the determination of a dissociation constant is not considered to be required (Guidance on information requirements and chemical safety assessment Chapter R.7a: Endpoint specific guidance, section R.7.1.17.1).

Key value for chemical safety assessment

Additional information