Registration Dossier
Registration Dossier
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EC number: 231-142-3 | CAS number: 7440-32-6
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
Description of key information
Titanium sponge powder (finest particle size distribution imported and used) has a mean particle size of 860µm. This sample shows a low dustiness (33.58 mg/g) and according to the MPPD model almost no deposition on the pulmonary region (PU) = 0.01% of the inhaled material.
Additional information
Based on the MPPD model, the following conclusions can be drawn for risk characterisation purposes:
(i) Titanium (metal powder) has a limited deposition ability in the human respiratory tract: less than 54 % of airborne material is estimated to deposit. The rest of the airborne material is either not inhaled at all due to physical phenomena related to air streams and turbulences close to the mouth or simply to the fact that particles are also exhaled (i.e. not deposited).
(ii) only about 0.01 % or less of inhaled material is predicted to be deposited in the pulmonary region (PU), whereas the material deposited in the tracheobronchial (TB) and the extrathoracic region (Head) may be assumed to be cleared to the GI tract (i.e., by mucociliary escalation and subsequent swallowing)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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