Registration Dossier
Registration Dossier
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EC number: 201-173-7 | CAS number: 79-06-1
Endpoint summary
Administrative data
Description of key information
Acrylamide induces peripheal neuropathy charcterized by a dying back of neurons. The NOAEL for this effect is 0.5 mg/kg/day as determined by light and electron microscopy. No clincal effects were obseved at 2.0 mg/kg/day, the next highest dose.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Dose descriptor:
- NOAEL
- 0.5 mg/kg bw/day
- Study duration:
- chronic
- Species:
- rat
Additional information
Justification for classification or non-classification
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