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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
up to 2006
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP status not known, guideline not known, information from a published handbook, acceptable with restrictions

Data source

Reference
Reference Type:
review article or handbook
Title:
The Merck Index. An encyclopedia of chemicals, drugs and biologicals. Fourteenth Edition.
Author:
O'Neil MJ (Ed.)
Year:
2006
Bibliographic source:
Merck & Co, Inc. Whitehouse Station, NJ, USA

Materials and methods

Principles of method if other than guideline:
The use of secondary sources of data is acceptable when they are based on a critical evaluation of peer-reviewed data and a consequent selection of a reliable and representative value for the property under investigation. The introduction to the Merck Index states that physical data are cited as found in the literature. When several alternate data values appear in the literature, the data is evaluated and representative selections are made; values are then reported with the corresponding source. Therefore, although the method used is not known, the values presented here are acceptable as they are from a reliable secondary source of phys chem. data.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
acetone
Solubility:
29.125 g/L
Temp.:
15 °C
Test substance stable:
yes
Details on results:
Acetone dissolves 25 vols acetylene at 15°C and 760 mmHg.

Applicant's summary and conclusion

Conclusions:
The solubility in acetone for the test substance is 29.125 g/L.
Executive summary:

The solubility in acetone for the test substance is 29.125 g/L. No information on the primary source of this data or the methods used is available.However, this information is taken from a reliable peer reviewed handbook and so can be considered reliable and suitable for use for this endpoint.