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EC number: 273-606-8
CAS number: 68990-52-3
The substance is not skin and eye irritating
Both studies for each end points on the
substance and on the analogous substance fatty acid rape oil methyl
esters showed a slight irritation after one hours completely reversible
in a few hours. The substance is then considered not irritant.
Effect level: empty Endpoint conclusion: Adverse effect observed
In general, esters of long-chain
fatty acids are always negative with relation to irritation (from C18
onward), while esters of short-chain fatty acids are always (slightly)
positive(up to C10). There are 2 relevant tests, for C16-C18and
C18unsaturated me esters and fatty acids, rape oil, me esters
, showing no irritation that support this conclusion. Eye irritation tests
are negative too and it is unlikely that a substance would be less
irritating to eyes than the skin.
However, as it is clear from literature
that shorter chain fatty acid me esters can cause skin irritation,
therefore this will need to be taken into account in the analysis.
Directive 67/548/EEC (DSD) states for substances containing individual
components then their classification should be taken into account when
determining the classification of a substance. This does not mean
automatically using the concentration limits set out in the DSD (for
irritation it is 20%) but that would be a useful starting point. If any
of the Biodiesel substances contained individual components causing
irritation at a concentration>20% then this would be the
starting point for any further analysis on irritation.
No classification for skin irritation
is warranted under 67/548/EEC or Regulation 1272/2008.
No classification for eye
irritation is warranted under 67/548/EEC or Regulation 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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