Registration Dossier
Registration Dossier
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EC number: 203-632-7 | CAS number: 108-95-2
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Phenol proved to be readily biodegradable. In two standardised tests for ready biodegradability (MITI-I-tests), levels of degradation amounting to between 60 and 70 % (after 4 days) and to 85 % (after 14 days) were determined. In a study conducted according to OECD guideline 305E under flow-through conditions and using Danio rerio as test organism, a BCF (total fish)=17.5 was calculated from kinetic parameters. Based on the results on short- and long-term toxicity of phenol to aquatic organisms, the lowest L(E)C50 were determined to be >1 mg/L in short-term toxicity testing and NOEC >0.01 mg/L in long-term toxicity testing. Based on the results on mammalian toxicity data of phenol, the substance does not meet the criteria for classification as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2) according to Regulation EC No 1272/2008. Based on the results on mammalian toxicity data of phenol, there is evidence of chronic toxicity that would meet the criteria for classification: STOT RE 1, or STOT RE 2 according to Regulation EC No 1272/2008. Therefore, the substance is to be regarded as a substance exhibiting T properties according to the criteria of REACH Directive, Article 14.3 (d) and the Technical Guidance Document (TGD) R.11 of the European Chemicals Agency.
Taken as a whole, these data indicate that phenol is not to be regarded as a substance exhibiting PBT or vPvB properties according to the criteria of REACH Directive, Article 14.3 (d) and the Technical Guidance Document (TGD) R.11 of the European Chemicals Agency.
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