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Short-term toxicity to aquatic invertebrates

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Description of key information

Key value for chemical safety assessment

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Read across justification

Several criteria justify the use of the read across approach to fill data gaps for paraffin and hydrocarbon waxes using other lubricant base oil analogs. Primarily the basis for the read-across is the similar physical chemical properties shared by the paraffin and hydrocarbon waxes and other lubricant base oils.

In a read-across key static 48-hour short-term Daphnia magna toxicity test (OECD 202; KS = 2), 10 animals/loading were exposed to the Water Accommodated Fraction (WAF) of an other lubricant base oil, MVI(N) 40 base oil (CAS # 64742-53-6 or 64741-97-5), at nominal concentrations of 0, 10, 100, 1000, and 10,000 mg/L. The EL50 was >10,000 mg/L and the NOEL was ≥ 1000 mg/L (Shell, 1988). 

 

In a read-across key semi-static 96-hour short-term freshwater shrimp (Gammarus pulex)toxicity test (OECD 202; KS = 2) to other lubricant base oils, 10 animals/loading were exposed to the WAF of an other lubricant base oil, MVI(N) 40 base oil (CAS # 64742-53-6 or 64741-97-5), at nominal concentrations 0, 10, 100, 1000, and 10,000 mg/L. The LL50 was >10,000 mg/L and the NOEL was ≥ 10,000 mg/L (Shell, 1988).

These studies are scientifically sound and satisfy the guideline requirements for short-term invertebrate tests. 

Supporting data estimated from the PETROTOX computer model show no acute toxicity of paraffin and hydrocarbon wax to freshwater fish at or below its maximum attainable water solubility (Redman et al., 2010b). These data support the applied read across.