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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

One key study and one supporting study have been identified as having assessed the short-term toxicity to aquatic invertebrates. The key study followed a guideline similar to the OECD guideline 202 and the supporting study followed the German Industrial Standard DIN38412 part 11 guideline.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
3 485 mg/L

Additional information

The key study followed a guideline similar to OECD 202, the concentrations (nominal) used were 0 (control), 1120, 1500, 2000, 2700, 3600, 4700, 6300 and 8400 ppm. This study concluded that the 48 h LC50 of tetrahydrofuran to daphnia magna is 3485 ppm. The supporting study followed the DIN38412 part 11 guideline but was conducted over a 24 hour exposure period and did not reveal the range of concentrations used. This study concluded that the 24 h LC50 was 5930 mg/l.