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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
other: supplemental information
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
publication
Title:
Altered Developmental Toxicity Caused by Three Carrier Solvents.
Author:
Rayburn, J.R., DeYoung, D.J., Bantle, J.A.
Year:
1991
Bibliographic source:
Journal of Applied Toxicology Vol. II(4), 253-260

Materials and methods

GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Results and discussion

Any other information on results incl. tables

The test substance only increased the mortality and malformation with TCE. There were additive effects for growth for all solvents with the teratogens. The carrier solvents caused interactions even at their NOEC.

Applicant's summary and conclusion