Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The 48-h EC50 value is > 10000 mg/L in aquatic invertebrates.

With high probability the test substance is acutely not toxic to aquatic invertebrates.

Key value for chemical safety assessment

Additional information

The acute toxicity to aquatic invertebrates was determined in a non-GLP study equivalent or similar to DIN 38412/11 (Bringmann & Kühn, 1982). In this study daphnids (D. magna, 20 per treatment) were exposed to the test substance up to 10000 mg/L (test concentrations not further specified), for 48 hours under static conditions. Analytical verification of the test concentrations was not performed (not specified). No detailed documentation on measured effect parameters or findings are available. No effect on mobility was observed. Based on the findings, the 48-h EC50 value was determined at > 10000 mg/L.

As supporting data, a publication is available that investigated the short-term toxicity to aquatic invertebrate in D. magna (Ziegenfuss et al., 1986). Test organisms were exposed to the test substance for 48 hours under freshwater static conditions. An 48-h EC50 for the test substance was determined to be 52400 mg/L based on mobility. Another publication is available that investigated the short-term mortality to D. magna (LeBlanc et al., 1983). Test organisms were exposed to the test substance for 48 hours under freshwater static conditions. An 48-h LC50 for the test substance was determined to be 35000 mg/L.

In addition, a supporting study is available that investigated the short-term toxicity to aquatic crustacea (Hyalella azteca) (PTAC, 2006). Test organisms were exposed to five test concentrations of the test substance and a control for 96 hours under freshwater static conditions. Analytical recovery of the test concentrations at test start and end were generally within 20% of nominal concentrations: 83-90%. Therefore, effect levels are reported as nominal. The 96-h LC50 for the test substance was determined to be 43500 mg/L.