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EC number: 203-953-2 | CAS number: 112-27-6
Readily biodegradable (according to OECD criteria).
The biodegradability of 2,2'-(Ethylenedioxy)diethanol is assessed in a weight-of-evidence approach. For 2,2'-(Ethylenedioxy)diethanol data from a MITI test (OECD 301C) is available (NITE Japan, 1992). Results varied between 25% and 92% degradation after 28 days, which indicates this substance is readily biodegradable.
Additionally, QSAR calculation using OASIS catalogic v22.214.171.124 reveal readily biodegradability of the test substance. In an OECD 301 C (Catalogic 301C v.11.15) 98% degradation was estimated and in an OECD 301B (Catalogic Kinetic 301B v.02.09) 80,9% degradation was estimated.
In conculsion 2,2'-(Ethylenedioxy)diethanol os assessed to be readily biodegradable.
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of CAS 112 -27 -6 (Q)SAR results were used for aerobic biodegradability in water. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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