Registration Dossier

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The 96-hour LC50 value of 5840 mg/L for sodium chloride was determined in a continuous flow-through exposure system with bluegill sunfish (Lepomis macrochirus).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
5 840 mg/L

Additional information

Four acute freshwater fish studies using four different fish species (bluegill sunfish, goldfish,tilapia, and fathead minnows) were listed for this endpoint. The study conducted with the bluegill sunfish was assigned a Klimish score of 1 since it followed guideline specifications and reported measured concentrations of the toxicant (NaCl). The acute toxicity test with the bluegill sunfish was conducted in a flow-through system and the 96 hour LC50 was 5,840 mg/L.  Two studies (conducted with nile tilapia and goldfish) were assigned Klimish scores of 2 based on good scientific practices followed in the studies, but without specific adherence to a guideline method. The acute toxicity test with goldfish was performed under semi-static conditions and the 96-hour LC50 for sodium chloride was 7341 mg/L. The acute toxicity test withtilapia fingerlings was performed under static conditions and the 96-hour LC50 for sodium chloride was 11,330 mg/L.  The acute toxicity study with the fathead minnow was assigned a Klimish score of 4 based on a lack of information provided in the report. The acute toxicity test with fathead minnows was performed under static conditions and the 96-hour LC50 for sodium chloride was 10,610 mg/L. Thus, the key parameter for the acute fish studies was the LC50 value of 5,840 mg/L for bluegill sunfish since this was the lowest reported LC50 value for sodium chloride.