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Toxicity to terrestrial arthropods

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Description of key information

A TLM-EqP modeling framework was used as key values to support experimental values derived experimentally and presented as supporting studies. The estimated 28 day LL50 values from TLM QSAR were 12.417 - 41.844 mg/kg dw and 28 day long-term effects NOELR values from TLM QSAR were 2.379 - 8.016 mg/kg dw.

Key value for chemical safety assessment

Additional information

Due to the technical challenges of testing volatile substances, a TLM-EqP modeling framework was used to support terrestrial effect values derived experimentally and are presented as supporting studies. These data were considered reliable and comparable to experimentally derived values; however, were not used in the PNEC derivation in order to comply with ECHA FDL (2014) on using experimental data to derive PNEC. The hazard to soil organisms was assessed by using the experimental data.

The Draft Screening Assessment Report (Environment Canada 2014) presented results from ESG International (2002) that found the toxicity of ethylbenzene to the collembola Onychiurus folsomi was a 14 day LC25 of 259 mg/kg dw (fine clay loam).

A TLM-EqP modeling framework was used to support experimental values derived experimentally and presented as supporting studies. The estimated 28 day LL50 values from TLM QSAR were 12.417 - 41.844 mg/kg dw and 28 day long-term effects NOELR values from TLM QSAR were 2.379 - 8.016 mg/kg dw.