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EC number: 203-458-1 | CAS number: 107-06-2
Based on a statistically significant reduction of fish weight the MATC (maximum acceptable toxicant concentration) of 1,2-dichloroethane in a fathead minnow early life stage test was 29 - 59 mg/L based on measured concentrations.
The key study was selected as the study shows the lowest toxicity endpoint.
The effects of 1,2-dichloroethane on the early life stages of fathead minnow (Pimephales promelas) were determined under continuous-flow conditions for 32 days. A dilution water control and nominal test item concentrations of 4.0, 7.0, 14.0, 29.0, and 59.0 mg/L were used during the study.
Based on a statistically significant reduction of fish weight the MATC (maximum acceptable toxicant concentration) of 1,2-dichloroethane in a fathead minnow early life stage test was 29 - 59 mg/L on measured concentrations.
Further on, the following additional information on long-term toxicity to fish is available, but is not considered as reliable:
56 mg/L (LOEC) after 21 d
Reid, B.J.et al.(1982)
0.2 mg/L after 27 d
Black, J.Aet al.(1982)
The effect values found by Black et al. for several substances are usually very low compared to effect values by other authors. No explanation for these large discrepancies could be found. A careful examination of the entire information provided by Black et al. gave no plausible reason for the inconsistency of the data. However, as it was not possible to reproduce the effect values found by Black and his co-workers, it is proposed not to use these data for a derivation of a PNECaqua if other valid fish early life stage tests are available.
Black, J.A. et al. (1982): NTIS/PB 82-224601.
Reid, B.J. Morgan J.D., Whelen, M.A. (1982): A preliminary examination of the effects of ethylene dichloride on the hatchability of coho salmon eggs (oncorhynchus kisutch); Can. Techn. Rep. Fish. Aquat. Sci. 1163, 145-153.
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