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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

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Administrative data

Description of key information

Two carcinogenicity studies with metallic iron were found in the public domain. In both studies very invasive and unnatural exposure routes were employed: the implantation of partly oxidized chips of iron or the intramuscular injection of iron powder in olive oil or trioctanoin. No clear indications for carcinogenicity were obtained, while in the same studies positive results were obtained with other metals applied by means of comparative techniques. The studies are disregarded because the application routes make them irrelevant in the present context.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Additional information