Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-000-3 | CAS number: 112-72-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009-10-02
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Remarks:
- Test procedure in accordance with national standard methods (ASTM) without GLP.
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM E 1148
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 1.3 mg/L
- Temp.:
- 23 °C
- pH:
- 5.5
- Remarks on result:
- other: Standard Deviation for these Data : +/- 0.6 mg/L
- Conclusions:
- A water solubility value of 1.3 mg/l at 23°C (slightly soluble) was determined for the substance using a relevant test method. The result is considered to be reliable.
- Executive summary:
Tetradecanol was determined according ASTM E 1148. The water solubility was determined to be 1.3 mg/l at 23 °C.
- Endpoint:
- water solubility
- Type of information:
- other: Data obtained from a handbook
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Principles of method if other than guideline:
- data is taken from a reliable handbook, information about the methodology is not available
- GLP compliance:
- not specified
- Water solubility:
- 0.31 mg/L
- Conclusions:
- A water solubility value of 0.31 mg/L was reported in a handbook which has been subject to peer-review and in which the original data sources are traceable. The result is considered to be reliable.
- Endpoint:
- water solubility
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- The value was predicted using a multiple partitioning model, supported by additional validation.
- Principles of method if other than guideline:
- Method: other: (calculated) partition model
- GLP compliance:
- no
- Water solubility:
- 0.2 mg/L
- Temp.:
- 25 °C
- Conclusions:
- A water solubility value of 0.2 mg/L was obtained at 25°C using an accepted calculation method. The result is considered to be reliable.
- Endpoint:
- water solubility
- Type of information:
- other: Data obtained from a secondary source
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- GLP compliance:
- not specified
- Water solubility:
- 0.31 mg/L
- Temp.:
- 25 °C
- Conclusions:
- A water solubility value of 0.31 mg/L was reported at 25°C in a secondary source to which reliability could not be assigned.
- Endpoint:
- water solubility
- Type of information:
- other: Data obtained from a collection of reliable data
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Principles of method if other than guideline:
- data is taken from a secondary source, information about the methodology is not available
- GLP compliance:
- not specified
- Water solubility:
- 0.191 mg/L
- Temp.:
- 25
- Conclusions:
- A water solubility value of 0.191 mg/L was reported at 25°C in a collection of reliable data which has been subject to peer-review and in which the original data sources are traceable. The result is considered to be reliable.
- Endpoint:
- water solubility
- Type of information:
- other: Data obtained from a collection of reliable data
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- GLP compliance:
- not specified
- Water solubility:
- 0.35 mg/L
- Temp.:
- 25 °C
- Conclusions:
- A water solubility value of 0.35 mg/L was reported at 25°C in a collection of reliable data which has been subject to peer-review and in which the original data sources are traceable. The result is considered to be reliable.
Referenceopen allclose all
Measurement
(triple determination)
Results: 1.5 mg/L / 1.0 mg/L / Not Detected
Mean Concentration in Water: 1.0 mg/L
Standard Deviation for These Data: ±0.6 mg/L
The water solubility is estimated to be 0.202 mg/l at a loading rate of 1000 mg/l.
Description of key information
The water solubility of a commercial sample of tetradecan-1-ol is 1.3 mg/L at 23°C and pH 5.5.
Key value for chemical safety assessment
- Water solubility:
- 1.3 mg/L
- at the temperature of:
- 23 °C
Additional information
A water solubility value of 1.3 mg/L at 23°C and pH 5.5 was determined with the use of a flask method in accordance with ASTM E 1148. The result is considered to be reliable.
It is supported by a value of 0.191 mg/L at 25°C, taken from a reliable and definitive reference source for solubility data (Yalkowsky and He, 2003), and consistent results from other reference sources. These results are supported by a predicted water solubility value of 0.2 mg/l at 25°C which was obtained for the substance using a validated QSAR estimation method
The value taken from literature for pure alcohol (0.191 mg/l) is used in exposure modelling.
All the available results indicate that tetradecan-1-ol is slightly soluble in water.
Discussion of trends in the Category of C6-24 linear and essentially-linear aliphatic alcohols:
As chain length increases, water solubility decreases, because the free energy required for a molecule to dissolve becomes less favourable for larger molecules.
Reference:
Yalkowsky,FH & He,Y. 2003. Handbook of Aqueous Solubility Data. CRC Press, Boca Raton, FL (ISBN 0-8493-1532-8)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
