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Long-term toxicity to aquatic invertebrates

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Description of key information

There is a MITI (1997) study for which not all the study design details are reported which describes an EC50 and NOEC of 4.0 mg/L and 3.2 mg/L, respectively. However, this result is higher than the short-term EC50 for aquatic invertebrates (0.62 mg/L). As the original study report has not been reviewed, there is insufficient information to determine the reason for this and therefore the study has been considered not to be reliable.

A QSAR estimate has been included to provide additional data for this endpoint. The estimated 21 day ChV is 0.812 mg/L, which is equivalent to a NOEC of 0.574 mg/L. The estimated NOELR values from TLM QSAR is 2.405 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
3.2 mg/L

Additional information

The toxicity data by the Environmental Agency of Japan (1997) has been cited in OECD SIDS but was unavailable for review. The study of chronic toxicity to Daphnia magna from Dicyclopentadiene over 21 days following OECD TG 202 (1984) showed NOEC 3.2 mg/L and LOEC 10 mg/L.

A QSAR estimate has been included to provide additional data for this endpoint. The estimated 21 day ChV is 0.812 mg/L, which is equivalent to a NOEC of 0.574 mg/L. The use of a QSAR model is considered suitable for this endpoint.

The long-term aquatic toxicity to this substance was estimated using the Target Lipid Model based on methodologies described by Mcgrath et al. (2004, 2015). The estimated NOELR for this substance is 2.405 mg/L.