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Data availability

For MAA acute as well as chronic studies of sufficient reliability are available for all three trophic levels and also reliable microbial toxicity data.


The aquatic toxicity of methacrylic acid was investigated on all three trophic levels using acute as well as long-term toxicity tests. The results showed that the test substance is of low toxicity to aquatic invertebrates (EC50 > 130 mg/L) and harmful to fish (LC50 85 mg/L) and algae(ECr50 45 mg/L). In the long-term toxicity tests, fish toxicity in an early life stages test with Danio rerio was the most sensitive endpoint with a NOEC of 10 mg/L, while a 21d Daphnia reproduction test had a NOEC of 53 mg/L. An investigation with a series of 12 marine species (fish, invertebrates, several algae) gave no indication of a higher sensitivity of marine species. To the contrary, LC/EC50 values and NOECs tended to be higher than the corresponding freshwater data.

The microbial EC10 was determined to be 100 mg/L based on growth inhibition of Pseudomonas putida.