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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

adsorption / desorption
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)

Data source

Reference Type:
study report
Report date:

Materials and methods

Test guideline
equivalent or similar to guideline
other: OECD 117
not specified
Principles of method if other than guideline:
The principle of the test method is similar to that of the OECD guideline no. 117: "Partition coefficient (n-octanol/water), high performance liquid chromatography (HPLC) method". While passing through the column along with the mobile phase the test substance interacts with the stationary phase. As a result of partitioning between mobile and stationary phases, the test substance is retarded. The dual composition of a cyanopropyl stationary phase, having polar and non-polar sites allows for interaction of polar and non-polar groups of a molecule in a similar way as is the case for organic matter in soil or sewage sludge matrices. This enables the relationship between the retention time on the column and the Koc on organic matter to be established.
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC estimation method
other: quartz

Test material

Constituent 1
Reference substance name:
2-aminoethanol, monoester with boric acid
EC Number:
EC Name:
2-aminoethanol, monoester with boric acid
Cas Number:
Molecular formula:
No IUPAC name is available for this UVCB substance
Details on test material:
- Name of test material (as cited in study report):MEA Polyborate
- Molecular formula (if other than submission substance):C2H7NO.xBH3O3
- Molecular weight (if other than submission substance):
- Smiles notation (if other than submission substance):
- InChl (if other than submission substance):
- Structural formula attached as image file (if other than submission substance): see Fig.
- Substance type:reaction product
- Physical state:liquid
- Analytical purity:100%
- Impurities (identity and concentrations):
- Composition of test material, percentage of components:40% salt in water and 68% salt in water
- Isomers composition:
- Purity test date:
- Lot/batch No.:EU-SMG 01695 & EU-SMG 01696
- Expiration date of the lot/batch:2011-04-02
- Radiochemical purity (if radiolabelling):
- Specific activity (if radiolabelling):
- Locations of the label (if radiolabelling):
- Expiration date of radiochemical substance (if radiolabelling):
- Stability under test conditions:STABLE
- Storage condition of test material:At room temperature in the dark
- Other:

Study design

Test temperature:
-2 °C

HPLC method

Details on study design: HPLC method:
- Apparatus:Agilent 7500CE (Agilent Technologies, Tokyo, Japan)
- Type:MicroMist
- Type, material and dimension of analytical (guard) column:Platinum
- Detection system:

- Type:
- Experiments with additives carried out on separate columns: yes / no
- pH:
- Solutes for dissolving test and reference substances:

- Method: by means of homologous series / by inert substances which are not retained by the column

- Identity:

- Quantity of test substance introduced in the column:
- Quantity of reference substances:
- Intervals of calibration:

- Number of determinations:

- Calculation of capacity factors k':
- Calculation of retention times:
- Determination of the log Koc value:

Batch equilibrium or other method

Analytical monitoring:
not specified

Results and discussion

Adsorption coefficient
log Koc
ca. 1.26

Any other information on results incl. tables

ICPMS chromatograms of the test substance solutions, the acetanilide reference solution (HPLC-UV chromatogram) and the corresponding blank solution are shown in Figures 1 - 3.


In the chromatograms of both test substance solutions, one peak was observed with a retention time of 140 seconds which is equivalent to a retention time of 1.96 minutes on the UV-detector. Under the same analytical conditions, the retention time of acetanilide (log Koc= 1.26) was 1.98 minutes on the UV-detector.


Hence, it was concluded that Polyborate does not significantly adsorb to soil.


Applicant's summary and conclusion

Validity criteria fulfilled:
In a GLP study, similar to OECD 117, the retention time of MEA Polyborate 1:3 was practically equivalent with the retention time of the reference substance, therefore the Koc of the reference substance (logKoc = 1.26) was taken as equivalent for MEA Polyborate 1:3.

Both substances, MEA Polyborate 1:1 and MEA Polyborate 1:3, consist of a MEA and a Polyborate part, both parts of both substances do not significantly adsorb to soil.

Both substances, MEA Polyborate 1:1 and MEA Polyborate 1:3, consist of a MEA and a Polyborate part, both parts of both substances do not significantly adsorb to soil.
Executive summary:

The aim of the study was to determine the adsorption coefficient (Koc) of MEA Polyborate 1:1 and MEA Polyborate 1:3on soil and on sewage sludge using high performance liquid chromatography (HPLC).


Both substances consist of a MEA and a Polyborate part, both parts of both substances do not significantly adsorb to soil.


In conclusion, both substances do not significantly adsorb to soil.