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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: acceptable study, meets basic scientific principles; restrictions: short observation period, brief report

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1966
Report Date:
1966

Materials and methods

Principles of method if other than guideline:
BASF-internal standards; estimation of the approximative LD50
GLP compliance:
no
Test type:
standard acute method
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
no data

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: aqueous emulsion resp. solution in olive oil
Details on oral exposure:
no information
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified
Details on study design:
Test substance given as a 2 - 50% aqueous emulsion with traganth resp. solution in olive oil.
Observation period: 7 days
Statistics:
no data

Results and discussion

Effect levelsopen allclose all
Dose descriptor:
approximate LD50
Effect level:
1 890 mg/kg bw
Remarks on result:
other: test with 2 - 50% aqueous emulsion with traganth
Dose descriptor:
approximate LD50
Effect level:
2 650 mg/kg bw
Remarks on result:
other: test with solution in olive oil
Mortality:
no data
Clinical signs:
Prone and lateral position, narcosis
Body weight:
no data
Gross pathology:
Nothing abnormal detected.

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU