Registration Dossier
Registration Dossier
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EC number: 202-849-4 | CAS number: 100-41-4
Toxicity to other aquatic organisms
Administrative data
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- other: Publication
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well-documented publication
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxic effects of endocrine disruptors on freshwater sponges: common developmental abnormalities
- Author:
- Hill, M. et al.
- Year:
- 2 002
- Bibliographic source:
- Environmental Pollution 117:295-300
Materials and methods
- Principles of method if other than guideline:
- Method: other
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Ethylbenzene
- EC Number:
- 202-849-4
- EC Name:
- Ethylbenzene
- Cas Number:
- 100-41-4
- Molecular formula:
- C8H10
- IUPAC Name:
- ethylbenzene
- Details on test material:
- IUCLID4 Test substance: other TS
Ethylbenzene
CAS No. 100-41-4
Purity: no data
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not applicable
Sampling and analysis
- Analytical monitoring:
- not specified
- Details on sampling:
- No data
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- No data
Test organisms
- Test organisms (species):
- other: other: freshwater sponge - Heteromyenia species and Eunapius fragilis
- Details on test organisms:
- No data
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 9 d
- Post exposure observation period:
- No data
Test conditions
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- Salinity:
- No data
- Nominal and measured concentrations:
- 0.03, 0.3 and 3 mg/l
- Details on test conditions:
- According to the author, no official standards mentioned.
The toxic effect of ethylbenzene was examined on growth and development of two species of freshwater sponge, Heteromyenia spec. and Eunapius fragilis.
Test concentrations: 0.03, 0.3 and 3 mg/l
Obeservation period: 3, 6 and 9 days - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 9 d
- Dose descriptor:
- EC100
- Effect conc.:
- 3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: germination
- Duration:
- 9 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: abnormal growth
- Details on results:
- At 0.3 mg/l abnormal growth in Heteromyenia species was observed. Sponges initiated germination, but produced a tight cluster (or tube) of cells that seemed to be exuded from the gemmule. Germination was completely inhibited at 3 mg/l
- Results with reference substance (positive control):
- No data
- Reported statistics and error estimates:
- No data
Any other information on results incl. tables
None
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- At 0.3 mg/l abnormal growth in Heteromyenia species was observed. Sponges initiated germination, but produced a tight cluster (or tube) of cells that seemed to be exuded from the gemmule. Germination was completely inhibited at 3 mg/l
- Executive summary:
The toxic effect of ethylbenzene was examined on growth and development of two species of freshwater sponge, Heteromyenia spec. and Eunapius fragilis.Test concentrations: 0.03, 0.3 and 3 mg/l Obeservation period: 3,6 and 9 days.
At 0.3 mg/l abnormal growth in Heteromyenia species was observed. Sponges initiated germination, but produced a tight cluster (or tube) of cells that seemed to be exuded from the gemmule. Germination was completely inhibited at 3 mg/l
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