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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Endpoint summary

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Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

A Local Lymph Node Assay (Huntingdon Life Sciences, 2010) was conducted to assess the potential of Fe3P to cause skin sensitization. The study was conducted according to OECD test guideline 429 and EC guideline B42, and in compliance with GLP.

Test groups of four mice per concentration were administered daily applications of 25 µL of vehicle (acetone : olive oil, 4:1 (v/v)), 25%, 50%, or100% w/v Fe3P in vehicle to the dorsal surface of both ears for three consecutive days. The proliferative response of the lymph node cells was then assessed five days after the initial application. Test control ratios (ratio of the proliferative response seen in test groups relative to the control group) were 0.7, 0.5, and 0.8 for the 25%, 50%, and 100% groups, respectively, and on this basis Fe3P is not considered to be a potential sensitizer.


Migrated from Short description of key information:
Local Lymph Node Assay: Not sensitising.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

The Local Lymph Node Assay (LLNA, Huntingdon Life Sciences, 2010) conducted on Fe3P concluded that it was not a potential sensitizer. On this basis, it may be stated conclusively that Fe3P should not be classified as a dermal sensitizer under either the CLP Regulation (1272/2008) or the Dangerous Substances Directive (67/548/EEC).