Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-539-3 | CAS number: 62-53-3
Endpoint summary
Administrative data
Description of key information
Additional information
There are no long term studies available on the toxicity of Aniline to soil macroorganisms, plants and microorganisms. However, for for plants there are various, valid short term toxicity tests that may be used for a derivation of PNECterrestic.
In EU-Risk Assessment Report (2004), Aniline, terrestrial risk assessment was performed in both, the atmospheric and soil compartment.
To allow the derivation of a PNECpIant for a risk assessment of the atmosphere, a plant fumigation test was performed with aniline (BASF, 2002). Three species of higher plants (Avena sativa, Brassica pekinensis and Abies grandis) were exposed in laboratory exposure chambers for 14 days to 3 aniline concentrations. The lowest NOEC of 0.3 mg/m3 found for Brassica pekinensis is used as basic value for the derivation of PNECplant. An assessment factor of 50 is proposed as the exposure period for the three tested plant species was only 14 days. Therefore PNECplant = 0.3 mg/m3 / 50 = 6 μg/m3.
The toxicity of aniline to Lactuca sativa in natural soil and in nutrient solution was tested in two short term toxicity tests. A 14-day EC50 for growth inhibition of 33 mg/kg soil (dw) and of 56 mg/kg soil (dw) was found. The lowest EC50 value found for soil exposure is used for the determination of the PNEC50. An assessment factor of 1,000 has to be applied. This leads to a PNECsoil of 33 μg/kg (dry weight).
Chronic data on three trophic levels for 3.4 Dichloroaniline were presented in EU-Risk Assessment Report (2004), Aniline. These results indicate that, toxicity of 3.4 TCA to soil organisms is strongly dependent on pre-incubation of the test substance into soil. Significantly higher effect values were observed in tests with soil pre-incubated for 2 -5 weeks than compared to freshly contaminated soils (Table 3.34, p. 54). It can be expected that 3.4 TCA reacts similar in soil as Aniline does, by forming covalent-bonds to humic acids. Under natural conditions, soil organisms will mainly be exposed to the bound substance, as Aniline is set free relatively slowly from the agents and is always in equilibrium with the bound form. Therfore, when performing further terrestrial tests, the binding properties of Aniline should be considered.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
