Registration Dossier

Administrative data

Description of key information

The key information for both skin and eye irritation of trisodium citrate found the substance not irritating (Roche, 1995; rel 1).

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

High reliability data on skin and eye irritation was available for trisodium citrate. The most recent studies were chosen as key. The supporting studies (Miles 1990, 1991; rel 1) are in accordance with the key information.

Justification for classification or non-classification

Based on the available information, there is no requirement for the classification or labelling of trisodium citrate for skin or eye irritation, in accordance with the current EU guideline.