Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 209-136-7 | CAS number: 556-67-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- Equilibration by slow-stirring (pure liquid substance in contact with distilled water).
- GLP compliance:
- no
- Type of method:
- other: Equilibration by slow-stirring
- Water solubility:
- 0.056 mg/L
- Temp.:
- 23 °C
- pH:
- ca. 7
- Details on results:
- Stable: no
Degradation products: yes
Degradation products (CAS No./EC No./EINECS Name): 1066-42-8 213-915-7 dimethylsilanediol - Conclusions:
- Interpretation of results: insoluble (< 0.1 mg/L)
A water solubility value of 0.0562 mg/L was determined at 23°C in a reliable study conducted according to generally accepted scientific principles.
Reference
Water solubility = 56.2 ug L-1 (190 x 10-9 mol L-1) at 23 °C
Description of key information
Water solubility [octamethylcyclotetrasiloxane]: 0.056 mg/l at 23°C
Key value for chemical safety assessment
- Water solubility:
- 0.056 mg/L
- at the temperature of:
- 23 °C
Additional information
Two reliable measured values for the solubility of the registration substance in freshwater are available. A water solubility value of 0.056 mg/l at 23°C was determined for the substance using equilibration by the slow-stirring method. The result is considered to be reliable and is selected as key study. This value is supported by a measure water solubility of 0.07 mg/l at 25°C using a relevant test method. The key study was selected as it is the most recent study and is in line with the UK RAR. In a secondary source to which reliability could not be assigned, a water solubility of 0.02 mg/l at 25°C was reported for the substance.
In synthetic seawater, the substance has a measured solubility of 0.033 mg/l at 25°C.
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