Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Toxicity to reproduction

Currently viewing:

Administrative data

Endpoint:
extended one-generation reproductive toxicity - basic test design (Cohorts 1A, and 1B without extension)
Study period:
Study in progress
Data waiving:
other justification
Justification for data waiving:
other:

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD TG 443 (extended one generation reproductive toxicity study). The information currently available from repeat dose and developmental toxicity does not suggest need for addition of cohort 3.

Test material

Constituent 1
Chemical structure
Reference substance name:
3-trimethoxysilylpropyl methacrylate
EC Number:
219-785-8
EC Name:
3-trimethoxysilylpropyl methacrylate
Cas Number:
2530-85-0
Molecular formula:
C10H20O5Si
IUPAC Name:
3-trimethoxysilylpropyl methacrylate
Test material form:
liquid

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: gavage

Results and discussion

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion