Registration Dossier
Registration Dossier
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EC number: 219-785-8 | CAS number: 2530-85-0
Endpoint summary
Administrative data
Description of key information
Additional information
Reliable short-term toxicity data are available for the registration substance, 3-trimethoxysilylpropyl methacrylate (CAS 2530-85-0, EC 219-785-8) to freshwater fish (Danio rerio, reported as: Brachydanio rerio), invertebrates (Daphnia magna) and algae (Desmodesmus subspicatus, reported as: Scenedesmus subspicatus). The relevant short-term values are:
Fish: LC50 (96 h): >83 mg/l, expressed in terms of the concentration of the silanol hydrolysis product, 3-(trihydroxysilyl)propyl methacrylate;
Daphnia: EC50 (48 h): >83 mg/l, expressed in terms of the concentration of the silanol hydrolysis product, 3-(trihydroxysilyl)propyl methacrylate;
Algae: EC50 (72 h): >83 mg/l and >445 mg/l; NOEC: =83 mg/l and ErC10 418 mg/l, expressed in terms of the concentration of the silanol hydrolysis product, 3-(trihydroxysilyl)propyl methacrylate.
An activated sludge respiration inhibition 3-hour EC50 value of >830 mg/l and NOEC value of =830 mg/l (nominal) were determined in a reliable study, expressed in terms of the concentration of the silanol hydrolysis product, 3-(trihydroxysilyl)propyl methacrylate.
The rapid hydrolysis of 3-trimethoxysilylpropyl methacrylate (half-life of 1.87 h at pH 7 and 20°C) means it is likely that the test organisms in each test were exposed primarily to the hydrolysis products of the substance, 3-(trihydroxysilyl)propyl methacrylate and methanol.
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