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Description of key information

Information regarding this endpoint was read-across to Alkyl (C12-C14) glycidyl ether (CAS 68609-97-2) to Alkyl (C13-C15) glycidyl ether (CAS 68081-84-5). Based on an activated sludge respiration inhibition test study, The 3-hour NOEC and IC50 for Alkyl (C13-C15) glycidyl ether is 100 mg/L and > 100 mg/L, respectively. A summary of a previous study perfomed on Alkyl (C12-C14) glycidyl ether is also available and reported no effects up to 10.000 mg/L.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
100 mg/L

Additional information

The read-across to alkyl (C12 -C14) glycidyl ether from alkyl (C13 -C15) glycidyl ether is appropriate for this endpoint as the use of surrogate data from a structurally similar chemical is considered to be acceptable. Furthermore, study results including physico-chemical properties, ecotoxicology and mammalian toxicology indicate similar characteristics.

In the activated sludge respiration inhibition test performed with alkyl (C13 -C15) glycidyl ether, the substance did not induce any inhibition of respiration of the activated sludge over a 3 -hour exposure. The 3 -hour IC50 was reported to be greater than 100 mg/L. The value of 100 mg/L was selected as key value for this endpoint.