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EC number: 271-846-8 | CAS number: 68609-97-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental Starting Date: February 23, 2010 and Experimental Completion Date: February 25, 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 3.77
- Temp.:
- 20 °C
- Remarks on result:
- other: PH was not indicated in the report
- Type:
- Pow
- Partition coefficient:
- 6 974.46
- Temp.:
- 20 °C
- Remarks on result:
- other: PH was not indicated in the report
- Conclusions:
- This study estimated the n-octanol/water partition coefficient (Log Pow) of the test substance,
Alkyl (C12-C14) glycidyl ether; CAS RN 68609-97-2, by gas chromatography (GC-FID). The
partition coefficient for Alkyl glycidyl ether was determined to be 6974.46, which corresponded to a
Log Pow of 3.77. - Executive summary:
The purpose of this study was to estimate the n-octanol/water partition coefficient (Log Pow) of the test substance, Alkyl (C12-C14) glycidyl ether; CAS RN 68609-97 -2, by gas chromatography (GC-FID). This study was conducted in accordance with OECD Guideline 107 using the methods described in the approved protocol and STILLMEADOW, Inc. SOPs. There were no
deviations from the protocol that affected the quality or outcome of the study.The partition coefficient for Alkyl glycidyl ether was determined to be 6974.46, which corresponded to a Log Pow of 3.77.
Reference
Description of key information
two studies were performed to estimate the n-octanol/water partition coefficient (Log Pow) of the test substance, Alkyl (C12-C14) glycidyl ether; CAS RN 68609-97 -2. One by gas chromatography (GC-FID), according to OECD Guideline 107, using 0.1g test substance dissolved in octanol. where he partition coefficient was determined to be 6974.46, which corresponded to a Log Pow of 3.77. Another study according to OECD Guideline 117, using 10 g test substance in 10mL n-octanol determined the log Pow to be >6.0 by estimating the solubility data in n-octanol and in water .
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6
- at the temperature of:
- 20 °C
Additional information
A study was performed to estimate the n-octanol/water partition coefficient (Log Pow) of the test substance, Alkyl (C12-C14) glycidyl ether; CAS RN 68609-97 -2, by gas chromatography (GC-FID). This study was conducted in accordance with OECD Guideline 107 using the methods described in the approved protocol and STILLMEADOW, Inc. SOPs. Approximately 0.1 g of Alkyl glycidyl ether was dissolved in approximately 30 ml equilibrated n-octanol. There were no deviations from the protocol that affected the quality or outcome of the study. The partition coefficient for Alkyl glycidyl ether was determined to be 6974.46, which corresponded to a Log Pow of 3.77.
Another study was performed to determine the partition coefficient log Pow of Oxirane, mono[(C12-14- alkyloxy)methyl] derivs. / ERC Nr 17 using the flask shaking method as described in OECD guideline no. 117, “Preliminary estimate of the partition coefficient”. About 10 g of test item was added to 10 mL of n-octanol. The solubility in water (performed in Study C81364) was found to be very poor and the solubility in n-octanol to be very high indicating a partition coefficient above 6. Hence, a main test according to OECD Guidelines 107/117 (either HPLC or flask shaking method) could not be applied. Therefore the partition coefficient of Oxirane, mono[(C12-14-alkyloxy)methyl] derivs. / ERC Nr 17 was estimated using the solubility data in n-octanol from the pre-test and in water from the main test (performed in Study C81364) and was found to be log Pow > 6.0.
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