Registration Dossier
Registration Dossier
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EC number: 203-905-0 | CAS number: 111-76-2
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
RELIABLE STUDY RESULTS:
Daphnia magna #1 (21 day NOEC, reproduction): 100mg/l
Daphnia magna #2 (21 day NOEC, reproduction): 100mg/l
Daphnia magna (21 day EC10, mortality): 134mg/l
Ceriodaphnia dubai (7 day, NOEC, reproduction): 56mg/l
Ceriodaphnia dubai (7 day, NOEC, mortality): 135mg/l
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Three chronic studies are available in invertebrates. All showed consistent results. The 21 day studies using daphnia magna are considered the most reliable as these are full guideline studies with no significant shortcomings. The third study in ceriodaphnia was only for 7 days and, whilst the NOEC for reproduction was slightly lower than for the first study, there was no clear dose response relationship observed which means some uncertainty is associated with the result. The two daphnia magna studies with idential results are therefore used for the key parameter. There is no chronic data available in saltwater species.
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