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EC number: 235-649-0
CAS number: 12410-14-9
The results of the epidermal exposures for the 50 % test substance
concentration to be tested in the main study are presented in table 1.
Based on these results, the highest test substance concentration
selected for the main study was a 50 % concentration.
See table 1 in the attached document “tables 1 +2”.
The slight erythema of the ears as shown by the animals treated at 50%
was considered not to have a toxicologically significant effect on the
activity of the nodes. No oedema was observed in any of the animals
All auricular lymph nodes of the animals of the experimental and control
groups were considered normal in size.
No macroscopic abnormalities of the surrounding area were noted in any
of the animals.
Body weights and body weight gain of experimental animals remained in
the same range as controls over the study period. The slight body weight
loss, noted in some animals, was considered not toxicologically
The mean DPM/animal value for the experimental group treated with test
substance concentrations 50 % was 1052 DPM and the mean DPM/animal value
for the vehicle control group was 1033 DPM.
No mortality occurred and no symptoms of systemic toxicity were observed
in the animals of the main study.
See table 2 in the attached document “tables 1 +2”
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