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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Substance specific information for the UVCB substance "Slags, precious metal refining" is not available for the endpoint "Genetic Toxicity". In order to meet the requirements for Annex VII till Annex X of Regulation (EC) 1907/2006, read across information from any constituents being relevant needs to be included. Due to the high number of constituents and variability in C&L of these constituents it was decided to use the classification information from the individual constituents and to calculate the resulting classification by using the “generic concentration limits of ingredients of a mixture classified as germ cell mutagens that trigger classification of the mixture.” and respective rules of Regulation (EC) 1272/2006 section 3.5.3.1 “Classification of mixtures when data are available for all ingredients or only for some ingredients of the mixture” with the MeClas tool. This approach has been presented and discussed with ECHA in several meetings.

In total, two different grades of "Slags, precious metal refining" (composition profile 1 – composition profile 2) were identified by the consortium that could be grouped according to their calculated C&L resulting from the specific composition profile. Thus, for "Slags, precious metal refining" one C&L entry for genetic toxicity (i.e., no C&L) was generated.


Short description of key information:
No information on animal testing of "Slags, precious metal refining" is available. Since, "Slags, precious metal refining" neither contains any constituent ≥ 0.1 % classified as mutagen Muta. 1, nor any constituent ≥ 1 % classified as mutagen Muta. 2, the substance does not require classification as germ cell mutagen.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

"Slags, precious metal refining" neither contains any constituent ≥ 0.1 % (w/w) classified as mutagen Muta. 1, nor any constituent ≥ 1 % (w/w) classified as mutagen Muta. 2. In conclusion, "Slags, precious metal refining" does not possess a mutagen and/or genotoxic potential in accordance with Regulation (EC) 1272/2008.