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EC number: 215-235-6 | CAS number: 1314-41-6
Under REACH (ECHA 2008, Chapter R.7B – Endpoint Specific Guidance), the term ‘Hydrolysis’ refers to the “Decomposition or degradation of a chemical by reaction with water”, and this as a function of pH (i.e., abiotic degradation). The need for testing may be waived if “The substance is highly insoluble in water”, or if “The substance is readily biodegradable”. The latter property of a substance assumes a rapid mineralization of the substance and therefore hydrolysis tests will provide little information.
In the case of the current substance - lead - the chemical safety assessment will be based on elemental metal concentrations, regardless of their (pH-dependent) speciation in the environment. Hence, as the assessment is based on the element concentration (i.e., Pb), physicochemical processes like decomposition and degradation by reaction with water are not relevant. Formation of different Pb-hydroxides may occur, but the chemical assessment will not make any differentiation among the different Pb-species (pooling of different speciation forms). This elemental-based assessment (pooling all speciation forms together) can be considered as a worst-case assumption for the chemical assessment. In general, (abiotic) degradation is an irrelevant process for inorganic substances that are assessed on an elemental basis.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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