Registration Dossier

Classification & Labelling & PBT assessment

DSD-DPD

General information

Name:
4,4'-methylenedianiline
Status:
67/548/EEC annex 1
Index number:
612-051-00-1
Remarks:
annex 1 including 31st ATP

Classification

Explosiveness

Reason for no classification:
conclusive but not sufficient for classification

Oxidising properties

Reason for no classification:
conclusive but not sufficient for classification

Flammability

Reason for no classification:
conclusive but not sufficient for classification

Thermal stability

Reason for no classification:
conclusive but not sufficient for classification

Acute toxicity

Reason for no classification:
conclusive but not sufficient for classification

Acute toxicity - irreversible damage after single exposure

Classification:
T; R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.

Repeated dose toxicity

Classification:
Xn; R48/20/21/22 Harmful: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed.

Irritation / corrosion

Reason for no classification:
conclusive but not sufficient for classification

Sensitisation

Classification:
R43 May cause sensitisation by skin contact.

Carcinogenicity

Classification:
Carc. Cat. 2; R45 May cause cancer.

Mutagenicity - genetic toxicity

Classification:
Muta. Cat. 3; R68 Possible risk of irreversible effects.

Toxicity to reproduction - fertility

Reason for no classification:
data lacking

Toxicity to reproduction - development

Reason for no classification:
data lacking

Toxicity to reproduction - breastfed babies

Reason for no classification:
data lacking

Environment

Classification:
N; R51/53 Dangerous for the environment; Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Labelling

Indication of danger

N - dangerous for the environment
T - toxic

Risk phrases

R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R43 - May cause sensitisation by skin contact
R45 - May cause cancer
R48/20/21/22 - Harmful: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R68 - Possible risk of irreversible effects

Safety phrases

S53 - avoid exposure - obtain special instructions before use
S45 - in case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
S61 - avoid release to the environment. refer to special instructions/safety data sheets

Specific concentration limits

Notes