Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 253-575-7 | CAS number: 37640-57-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Very little other information than the LD50 value is reported.
Data source
Reference
- Reference Type:
- publication
- Title:
- Melamine cyanurate, melamine and cyanuric acid: toxicological characteristics
- Author:
- Babayan EV and Aleksandryan AV
- Year:
- 1 985
- Bibliographic source:
- Zhurnal Eksperimental Nov Kunicheskoi Meditsiny 25 (4), 345 - 349
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- No experimental details available that would allow concluding on similarity to available guidelines.
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- 1,3,5-triazine-2,4,6(1H,3H,5H)-trione, compound with 1,3,5-triazine-2,4,6-triamine (1:1)
- EC Number:
- 253-575-7
- EC Name:
- 1,3,5-triazine-2,4,6(1H,3H,5H)-trione, compound with 1,3,5-triazine-2,4,6-triamine (1:1)
- Cas Number:
- 37640-57-6
- Molecular formula:
- C3H6N6.C3H3N3O3
- IUPAC Name:
- 1,3,5-triazinane-2,4,6-trione - 1,3,5-triazine-2,4,6-triamine (1:1)
- Test material form:
- not specified
- Details on test material:
- No details are given.
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- water
- Details on dermal exposure:
- The aqueous suspension was applied onto shaved skin.
- Duration of exposure:
- no data
- Doses:
- 1 - 10 g per kg bw
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 5 525 mg/kg bw
- Remarks on result:
- other: +/- 158 mg/kg bw
- Mortality:
- yes
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
