Hydrocarbons, C10, aromatics, >1% naphthalene

Endpoint summary

Description of key information

There is data available for this substance. Additionally, key and supporting data is available for the following structural analogues: Hydrocarbons, C10-C13, aromatics, <1% naphthalene and Hydrocarbons, C10-C13, aromatics, >1% naphthalene. The data for these substances is presented in the dossier. The data is read across to these substances based on analogue read across and a discussion and report on the read across strategy is provided as an attachment in IUCLID Section 13.

There was no experimental data available for this substance or structural analogues for long-term toxicity to fish, long-term toxicity to aquatic invertebrates, and toxicity to microorganisms. For these endpoints, the aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

The substances are poorly soluble and made of constituents with various water solubility. As a consequence, the exposures were performed with Water Accommodated Fractions (WAFs). Therefore, the results are based on nominal loadings.

According to the harmonised CLP legislation (2008), Annex VI, this substance is classified for the environment as aquatic chronic category 2 with the hazard statement H411: Toxic to aquatic life with long lasting effects.

Additional information

Key data is summarised below:

Short-term toxicity to fish

Hydrocarbons, C10-C13, aromatics, <1% naphthalene, presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of 3.6 mg/L.

 

Hydrocarbons, C10, aromatics, >1% naphthalene presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of between 2 and 5 mg/L

 

Hydrocarbons, C10-C13, aromatics, >1% naphthalene, presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of 3.0 mg/L.

 

Long-term toxicity to fish

The aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

Short-term toxicity to aquatic invertebrates

Hydrocarbons, C10, aromatics, >1% naphthalene, presented a 48-h EL50 (mobility) for Daphnia magna of between 3 and 10 mg/L (WAF).

Hydrocarbons, C10-C13, aromatics, >1% naphthalene, presented a 48-h EL50 (mobility) for Daphnia magna of 1.1 mg/L (WAF).

Long-term toxicity to aquatic invertebrates

The aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

Toxicity to algae and cyanobacteria

Water accommodated fractions of hydrocarbons, C10-C13, aromatics, >1% naphthalene, presented a 72-hour EL50 value for Pseudokirchneriella subcapitata of 3.8 mg/l and 7.9 mg/l based on biomass and growth rate, respectively. The 72-hour NOELR (No Observed Effect Loading Rate) value for Pseudokirchneriella subcapitata is 0.22 mg/l based on both growth rate and biomass.

 

Water accommodated fractions of Hydrocarbons, C10, aromatics, >1% naphthalene, presented a 72-hr EL50 value for Pseudokirchneriella subcapitata of between 1.0 to 3.0 mg/l based on both growth rate and biomass. The 72-hr NOELR (No Observed Effect Loading Rate) value for Pseudokirchneriella subcapitata is approximately 1.0 mg/l based on both growth rate and biomass

Toxicity to microorganisms

The aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.