Registration Dossier

Classification & Labelling & PBT assessment

GHS

General Information

Name:
sodium hypophosphite
Implementation:
EU
Remarks:
The classification reported below is according to the European regulation 1272/2008 (CLP regulation). As no harmonised classification of sodium hypophosphite is available in Annex VI of the CLP regulation (EC) n° 1272/2008, the substance is self classified.
Physical hazards:
- Sodium hypophosphite is an inorganic solid; therefore the physical hazard statements for liquids and gases are not relevant. In these cases, the reason for no classification is equal to "conclusive but not sufficient for classification". This was the case for: “Flammable gases”, “Flammable aerosols”, “Oxidising gases”, “Gases under pressure”, “Flammable liquids”, “Pyrophoric liquids” and “Oxidising liquids”.
- Sodium hypophosphite could not be classified in accordance with the classification criteria of the CLP regulation (EC) n°1272/2008 as a result of the molecular structure of the substance for following physical hazards:
“Explosives”: On the basis of functional groups that may have explosive properties (Bretheriek's handbook of Reactive Chemical Hazards, Butterworths, 4th Edition), it is possible to exclude beyond reasonable doubt that monohydrated sodium hypophosphite has explosive properties. Moreover, this substance is not classified according to UN regulation on transport of dangerous goods which supports the statement above made on the basis of functional groups.
“Oxidising solids”: According to the chemical structure it is possible to exclude beyond reasonable doubt that this substance has oxidising properties. Furthermore the test substance is not classified according to the UN classification for the transport of dangerous goods confirming the conclusion based on the chemical structure regarding the absence of oxidising properties.
“Organic peroxides”: based on the molecular structure of the test substance and the classification criteria of the CLP regulation it is clear that sodium hypophosphite cannot be classified as organic peroxide.
- Sodium hypophosphite could not be classified in accordance with the classification criteria of the CLP regulation (EC) n°1272/2008 as a result common knowledge based on current uses and industrial experiences for the following physical hazards:
“Self-reactive substances and mixtures”: according to actual knowledge during use and storage, monohydrate sodium hypophosphite is stable. Moreover a small scale ARC testing (non-guideline) suggests that Self-Accelerating Decomposition Temperature (SADT) for 50kg package will be greatly above 75°C.
“Pyrophoric solids”: The substance does not ignite within 5 minutes after exposure to air and is therefore not pyrophoric. Indeed, Melting Point and ATG were carried out in the presence of air, moreover current practices showed that handled under air is stable with no evidence of instability.
“Self-heating substances and mixtures”: according to ARC and self ignition tests it appears that thermal instability starts at high temperature (238°C). Therefore sodium hypophosphite is considered to be stable at 140°C (i.e. not self heating).
“Substances and mixtures which in contact with water emit flammable gases”: According to hydrolysis study, sodium hypophosphite is soluble and stable in water. In consequence the substance is not considered as a substance which emits flammable gases when in contact with water.
“Substances and mixtures corrosive to metals”: Considereing that sodium hypophosphite is a reducing agent and its pH is 7, these two properties exclude any corrosivity to metal. To actual knowledge, no historical corrosivity of the substance to metal is recorded.
To actual knowledge, no historical corrosivity of the substance to metal is recorded. Moreover, based on the actual main use of sodium hypophosphite as reduction agent in electroless nickel and copper plating of metal, the substance is considered as not corrosive to metal.
Health hazards
- Following,Health hazards were flagged with "data lacking" as there is insufficient data to classify sodium hypophosphite: “Acute toxicity - inhalation”, “Respiratory sensitization”, “Aspiration hazard” and “carcinogenicity”.
- “specific target organ toxicity – single”: no specific test is available however the repeated dose toxicity test shows that no effect is observed, therefore it is considered as conclusive but not sufficient for classification.

Related composition

Related composition:
Composition 5

Classificationopen allclose all

Explosives
Reason for no classification:
conclusive but not sufficient for classification
Flammable gases and chemically unstable gases
Reason for no classification:
conclusive but not sufficient for classification
Aerosols
Reason for no classification:
conclusive but not sufficient for classification
Oxidising gases
Reason for no classification:
conclusive but not sufficient for classification
Gases under pressure
Reason for no classification:
conclusive but not sufficient for classification
Flammable liquids
Reason for no classification:
conclusive but not sufficient for classification
Flammable solids
Reason for no classification:
conclusive but not sufficient for classification
Self-reactive substances and mixtures
Reason for no classification:
conclusive but not sufficient for classification
Pyrophoric liquids
Reason for no classification:
conclusive but not sufficient for classification
Pyrophoric solids
Reason for no classification:
conclusive but not sufficient for classification
Self-heating substances and mixtures
Reason for no classification:
conclusive but not sufficient for classification
Substances and mixtures which in contact with water emit flammable gases
Reason for no classification:
conclusive but not sufficient for classification
Oxidising liquids
Reason for no classification:
conclusive but not sufficient for classification
Oxidising solids
Reason for no classification:
conclusive but not sufficient for classification
Organic peroxides
Reason for no classification:
conclusive but not sufficient for classification
Corrosive to metals
Reason for no classification:
conclusive but not sufficient for classification
Desensitized explosives
Reason for no classification:
data lacking
Acute toxicity - oral
Reason for no classification:
conclusive but not sufficient for classification
Acute toxicity - dermal
Reason for no classification:
conclusive but not sufficient for classification
Acute toxicity - inhalation
Reason for no classification:
data lacking
Skin corrosion / irritation
Reason for no classification:
conclusive but not sufficient for classification
Serious eye damage / eye irritation
Reason for no classification:
conclusive but not sufficient for classification
Respiratory sensitisation
Reason for no classification:
data lacking
Skin sensitisation
Reason for no classification:
conclusive but not sufficient for classification
Aspiration hazard
Reason for no classification:
data lacking
Reproductive toxicity
Reason for no classification:
conclusive but not sufficient for classification
Effects on or via lactation
Reason for no classification:
conclusive but not sufficient for classification
Germ cell mutagenicity
Reason for no classification:
conclusive but not sufficient for classification
Carcinogenicity
Reason for no classification:
data lacking
1. Specific target organ toxicity - single
Reason for no classification:
conclusive but not sufficient for classification
1. Specific target organ toxicity - repeated
Reason for no classification:
conclusive but not sufficient for classification
Hazardous to the aquatic environment (acute / short-term)
Reason for no classification:
conclusive but not sufficient for classification
Hazardous to the aquatic environment (long-term)
Reason for no classification:
conclusive but not sufficient for classification
Hazardous to the ozone layer
Reason for no classification:
data lacking

Labelling

Signal word:
No signal word

Notes